Medicines to Prevent Bone Disease
Keeping Your Bones Healthy
To learn about what to eat to maintain the right amounts of calcium and phosphorus, visit the Nutrition Room.
Key Players in Bone Disease
Healthy kidneys turn vitamin D from food (and the sun) into the active form your body needs. But, if your kidneys don’t work well, you may not have enough active vitamin D.
Without active vitamin D, your body can’t keep the right balance of calcium and phosphorus in your blood.
Your calcium levels will get too low
Your phosphorus levels will get too high
Tiny parathyroid glands in your neck will make parathyroid hormone (PTH) to try to boost the levels of calcium in your blood. But, this won’t work if you have too much phosphorus in your blood.
A vicious cycle begins. If it keeps up, your bones could get weak and break more easily.
Vitamin D May Be Given by Mouth or Injection
MANY Americans don’t have enough vitamin D, even if their kidneys are fine. The good news is, not having enough vitamin D is a problem that is easy to treat. Your doctor may ask you to take over-the-counter vitamin D pills or softgels. Or, he or she may prescribe active vitamin D. This may be given as pills or as injections.
Having the right amount of vitamin D in your blood will shut off the extra PTH so you don’t lose as much calcium out of your bones. Your blood levels of calcium will be checked to be sure they don’t go too high.
Medicine to Reduce Your PTH Levels
In some cases, vitamin D is not enough to shut off the excess parathyroid hormone. Your parathyroid glands grow larger as they struggle to keep making more PTH. In time, they can get so big that they can’t shut off. In the past, surgery had to be done to remove the glands. But now, a pill called cinacalcet can help shut off excess PTH. Your doctor may prescribe this drug for you if your PTH levels are too high.
Most of the side effects of cinacalcet are minor, like upset stomach. But some can be serious. Tell your doctor about any symptoms you have after you start ANY drug. If you take cinacalcet, be sure to call the doctor right away if you have:
- Burning or tingling of your lips, tongue, fingers, or feet
- Muscle aches or cramps, or a sudden tight feeling in the muscles of your hands, feet, face, or throat
Medications to Prevent Bone Disease
Vitamin D helps you make strong bones and keeps calcium and _____ at the right levels in your blood:
Not scored Calcium and phosphorus work together in your body. When your blood calcium levels are right, your phosphorus levels tend to be right, too.
Your gut can’t absorb calcium from food if you don’t have enough active vitamin D:
Not scored Without enough active vitamin D, you could eat lots of calcium, but your gut would not be able to absorb it.
Your parathyroid glands can be found:
Not scored Most people have four small parathyroid glands in their thyroid gland, in the neck.
Having too much parathyroid hormone (PTH) in your blood can lead to:
Not scored PTH tells your bones to release calcium into your blood. Over time, losing too much calcium can make your bones weak and more likely to break.
If vitamin D alone is not enough to shut off excess PTH, other treatments are:
Not scored Cinacalcet is a drug that acts on the parathyroid glands to shut them off. If it doesn’t work, surgery may be needed to remove the glands.